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An unusual case report on the possible role of Warfarin in migraine prophylaxis

Angelo Russo, S. Santi, D. Gueraldi, M. De Paola, F. Zani, L. Pini

SpringerPlus, 2013

13 citations

Abstract

BackgroundMigraine is a complex disease whose physiopathological mechanisms are still not completely revealed.FindingsWe describe an unusual case, not yet described in literature, of a patient who reported migraine remission, but still presented aura attacks, since starting a therapy with Warfarin.ConclusionsThis case report brings out new questions on the role of the coagulation, especially the blood coagulation pathway, in migraine with aura pathogenesis, and on the possibility to use vitamin K synthesis inhibitors, Warfarin or new generation drugs, as possible therapy to use in migraine prophylaxis.

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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