Therapeutic strategies for benign paroxysmal positional vertigo of the Japan Society for Equilibrium Research
Abstract
OBJECTIVE: The Japan Society for Equilibrium Research (JSER) published the Japanese Clinical Practice Guideline for Benign Paroxysmal Positional Vertigo (BPPV) 2023 to propose therapeutic strategies for BPPV. This review focuses on clinical questions (CQs) and treatment recommendations of the guideline.
METHODS: The Committee for Clinical Practice Guidelines of JSER formulated CQs related to the treatment of BPPV in accordance with the Minds Manual for Guideline Development 2020 and conducted a structured literature search. A systematic review was carried out to evaluate the quality of evidence, and the recommendation statements, recommendation levels, evidence levels, and references were decided.
RESULTS: The Committee for Clinical Practice Guidelines of JSER formulated 10 CQs concerning the efficacy of the canalith repositioning procedure (CRP) with adjunctive maneuvers, medical and surgical treatments, natural history and risk factors of BPPV, and proposed recommendation statements to answer the CQs with levels of evidence and recommendation.
CONCLUSION: The CRP is strongly recommended for the treatment of BPPV. Mastoid vibration during the CRP and postural restriction after the CRP have no additional effects. Because BPPV is self-limited, observation without the CRP is acceptable for 1 week after the onset. Risk factors for the development of BPPV include female sex, a low serum vitamin D level, osteoporosis, migraine, head trauma, and a high total cholesterol level.…
How strong is the evidence?
Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
Read the paper
Related studies
- Calcium Ions in the Physiology and Pathology of the Central Nervous System
- AI-powered in silico twins: redefining precision medicine through simulation, personalization, and predictive healthcare
- In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene
- In Silico drug repurposing pipeline using deep learning and structure based approaches in epilepsy
- Targeting serotonin receptors with phytochemicals – an in-silico study
- In silico exploration of anti-prostate cancer compounds from differential expressed genes
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.