Clinical Study of Evaluating the Efficacy of Zinc Supplementation as Adjuvant Therapy for Severe Pneumonia in Young Children
Abstract
Background: Pneumonia is described as an inflammation of the lung parenchyma. 1 Pneumonia is a major cause of illness and death in children worldwide, particularly in children under the age of five. Moreover, Preventive zinc supplementation may repair any deficiency that leads to immunodeficiency, and some data showed that it may lower child mortality and morbidity from infectious illnesses, including diarrhoea and pneumonia. Objective: In this study our main goal is to evaluate the efficacy of zinc supplementation as adjuvant therapy for severe pneumonia in young children. Method: This case control observational study was carried out at Tertiary medical college and hospital from June 2020 to 2021 among 200 young children aged <2 months to 5 years suffering from pneumonia. The participants were randomly assigned, following simple randomization procedures (1: 1), to receive zinc or placebo (5 mL every 12 hours) along with the common antibiotic treatments until discharge, was considered as a zinc supplement group, n=100. Patient assigned to placebo received the same solution as zinc supplement syrup but without zinc, which was considered as a non-zinc group, n=100. Results: During the study, maximum numbers of study group were in the age group 6 months to 2 years (56%) and (52%). Plus, in both group majority were male. In both group cough complaints was common, 100%. In zinc therapy group all had fever and hurried breathing and 9.6% had cold. Where as in non-zinc group all had…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 200 participants or records.
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