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P-1685. Knowledge, Attitudes, and Practice of Healthcare Providers Regarding Oral Antibiotic Use in a Health System

Emily Gammill, Emily Shephard, Hita Bhagat, Dominic Chan

Open Forum Infectious Diseases, 2025

224 participants

Abstract

Abstract Background Treating infections with oral (PO) antibiotics is associated with reduced risk for catheter associated infections, costs, and length of stay. However, barriers in appropriate transition to PO antibiotics exist. Intravenous versus oral antibiotics by treatment indication The most common treatment indications were pneumonia, cellulitis, bacteremia, and urinary tract infection. A lower proportion of patients with cystitis and bacteremia were transitioned to oral antibiotics compared to other indications. Methods This study aims to understand the knowledge, attitudes, and practice of healthcare providers regarding PO antibiotics. This is a cross-sectional, descriptive survey followed by a multi-center, retrospective chart review. A web-based questionnaire was distributed electronically and promoted during meetings to healthcare providers. The retrospective chart review included admitted adult patients who were administered antibiotics for targeted infections. Patients that were pregnant, incarcerated, had inadequate PO absorption, or lack of source control were excluded. The primary outcome was to identify areas for antimicrobial stewardship intervention. This was done by identifying discordances between provider knowledge or attitudes and prescribing practices. Descriptive statistics and regression analyses were conducted. Results The survey collected 119 total responses from pharmacists (47.1%), physicians (36.1%), medical residents (5.9%), and advanced…

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