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Migraine and pregnancy : Gender-specific aspects and current knowledge

Raffaelli B, Lange KS

Der Nervenarzt, 2024

Abstract

BACKGROUND: Migraine, a frequent and debilitating neurological disease, shows gender-specific differences in prevalence and severity. Pregnancy is associated with numerous unique features in terms of migraine course, treatment options and differential diagnoses.

OBJECTIVES: How does pregnancy influence the course of migraine? What are the possible treatment options during pregnancy? Which differential diagnoses should be considered?

MATERIAL AND METHODS: Narrative review with summary and discussion of relevant studies and guidelines on migraine in pregnancy.

RESULTS: During pregnancy up to three quarters of women experience improvement of their migraine; however, there may be a renewed increase in frequency after childbirth. Choosing an appropriate treatment during pregnancy requires a careful risk-benefit assessment. It is important to consider secondary causes of headache as these can occur more frequently during pregnancy and some can be life-threatening.

CONCLUSION: Consideration of specific aspects of migraine in pregnancy is crucial to be able to develop the best possible treatment strategies for affected patients.

ZUSAMMENFASSUNG: HINTERGRUND: Migräne, eine häufige und beeinträchtigende neurologische Erkrankung, zeigt geschlechtsspezifische Unterschiede in Prävalenz und Schweregrad. Die Schwangerschaft geht mit zahlreichen Besonderheiten in Bezug auf Migräneverlauf, Therapieoptionen und Differenzialdiagnosen einher.

FRAGESTELLUNGEN: Wie beeinflusst eine…

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