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The effectiveness of clinical hypnosis on migraine headache symptoms and pain perception

Beit-Mashal B, Khodarahimi S, Haghighat A, Javanbakht F, Rahimian Bougar M, Mirghobad Khodarahmi S, Hoor A

The American journal of clinical hypnosis, 2026

Abstract

This study examined the effectiveness of the Hypnotherapy Protocol for Migraine in Adults (HPMA) in alleviating pain perception and migraine symptoms among outpatients. It was designed as a randomized controlled trial comprising three phases: baseline, intervention, and follow-up, which included both an experimental group and a wait-list control group. The sample consisted of 40 outpatients from Iran, categorized into those with aura, those without aura, and those with chronic migraine, selected through random sampling for each group. The research employed the Short-Form McGill Pain Questionnaire (SF-MPQ;) and the Ahvaz Migraine Questionnaire (AMQ;) for assessment. The experimental group underwent 10 sessions of HPMA, scheduled biweekly, with each session lasting 60 minutes. The analysis indicated that the experimental group showed a significant reduction in pain perception (including sensory, affective, and total scores of SF-MPQ) and migraine symptoms when compared to the wait-list control group during both the intervention and follow-up phases.

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Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design.

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