Pelvic infections with intrauterine device: microbiological profile and clinical significance
Abstract
Intrauterine devices (IUDs) are widely used long-acting method of reversible contraception which has a high efficacy and safety. Around the world, about 22.8% of women use IUDs for birth control. However, the use of these devices is highly associated with an increased risk of pelvic inflammatory diseases, potentially leading to significant health complications.The objective: to identify the prevalence of bacterial microorganisms in endocervical swabs from women using IUDs and assess the antibiotic sensitivity profiles of these isolates.Materials and methods. This research is a cross-sectional study starting from June 2022 and ending in June 2024. Both written and verbal consents of 162 women aged 18–48 years who used IUDs as a contraceptive method and attended the private gynecology clinic and Al-Zahrawi hospital in Mosul city, Iraq were provided. Endocervical vaginal swabs were taken and diagnosed by Gram staining method, biochemical testing, and the VITEK 2 system for bacterial identification. Antibiotic sensitivity was assessed using automated methods.Results. Among the 162 participants, 90 (55.56%) women had negative culture results, while 72 (44.44%) patients had positive results. Escherichia coli was the predominant microorganism (17.28%), followed by Klebsiella spp. (6.79%) and Staphylococcus aureus (7.41%). Antibiotic sensitivity test has revealed that meropenem, imipenem, levofloxacin, and colistin were the most effective medications, showing 100% sensitivity. Other…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 162 participants or records.
Read the paper
Related studies
- Penicillins for Treatment of Pneumococcal Pneumonia: Does In Vitro Resistance Really Matter?
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations
- GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach
- Propranolol, chlorpromazine and diclofenac restore susceptibility of extensively drug-resistant (XDR)-Acinetobacter baumannii to fluoroquinolones
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.