A Randomized Controlled Pilot Exploratory Study on the Impact of Cessation of Toothpaste in Patients With Migraine Headaches
Abstract
Certain ingredients in toothpaste have the potential to cause headache. In this clinical trial, the investigators will be replacing toothpaste with saline water in a group of persons with migraine and compare them with another group of persons with migraine who will continue the use of toothpaste.
Both the groups will have the same treatment protocol with the only difference being the intervention of changing the toothpaste with saline.
This study will show whether this lifestyle intervention can improve headache frequency in persons with migraine over a four week period.
Conditions: Migraine.
Primary outcome: Headache frequency.
Enrollment: 106 participants.
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 106 participants or records.
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