Outcome and Severity of COVID-19 in Vaccinated and Unvaccinated patients
Abstract
Background: The coronavirus disease of 2019 (COVID-19) pandemic is the world's worst problem and the global health disaster of our time. In order to fully comprehend the advantages of COVID-19 immunization, illness attenuation must be considered. This should be done by investigating whether those who contract COVID-19 despite vaccination experience milder symptoms than those who are unvaccinated. The COVID-19 pandemic brought on by is still a serious public health issue on a global scale. Aim: To evaluate the significant impact and efficacy of vaccination in positive SARS-CoV-2 patients during different timelines of a pandemic. Methodology: This is a cross sectional study involving 212 PCR-positive SARS-CoV-2 patients with their clinical–epidemiological findings admitted at Ziauddin Hospital between the years 2021 to 2022. SARS-CoV-2. RNA positivity was determined using qualitative RT-PCR with in vitro diagnostic kits, following the manufacturer's recommendations. SARS-CoV-2 positive patients had at least one positive RT-PCR test result, while SARS-CoV-2 negative patients had solely negative RT-PCR test findings. The data was provided through electronic patient records. The patients were categorized into Asymptomatic, Mild, Moderate and Severe/Critical as per WHO and CDC guidelines. Results: Among total of 212 patients there were 5(2.4%) vaccinated and 20(9.4%) unvaccinated asymptomatic, 6(2.8%) vaccinated and 12(5.7%) unvaccinated mild, 16(7.5%) vaccinated and 39(18.4%)…
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