P-56. Clinical and Microbiological Profile of Enterococcal Bacteremia in a Tertiary Hospital in the Dominican Republic
Abstract
Abstract Background Enterococcal bacteremia is an emerging concern in hospitalized patients, often associated with multidrug resistance and high morbidity. Limited data exists in the Dominican Republic on its clinical features and outcomes. Antimicrobial resistance patterns by Enterococcus Species Types of Enterococcus Methods A retrospective cross-sectional study was conducted at Hospital General Plaza de la Salud from January 2022 to December 2023. Medical records were reviewed to collect demographic, clinical, microbiological, and outcome data on patients with blood culture–confirmed Enterococcus spp. bacteremia. Results Seventy-one patients were included, predominantly male (64.7%), with a median age distribution favoring patients over 60 years (64.7%). Comorbidities included chronic kidney disease (43.6%), diabetes (36.6%), and hypertension (18%). Most cases (70.4%) were nosocomial. E faecalis accounted for 92.9% of isolates, followed by E. faecium (5.6%) and E. gallinarum (1.4%). High resistance rates were noted for tetracycline (80.3%), erythromycin (59.1%), and gentamicin (54.5%) among E. faecalis isolates, while 50% of E. faecium isolates showed resistance to ampicillin, linezolid, and daptomycin (Figure 1). No vancomycin resistance was detected. Vancomycin and ampicillin were the most commonly used treatments, with 70.8% achieving negative blood cultures within 7 days. Bacteremia recurrence occurred in 11.1% of cases. Complications included sepsis (28.1%),…
Read the paper
Related studies
- Penicillins for Treatment of Pneumococcal Pneumonia: Does In Vitro Resistance Really Matter?
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Development and validation of microbial bioassay for quantification of Levofloxacin in pharmaceutical preparations
- GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach
- Propranolol, chlorpromazine and diclofenac restore susceptibility of extensively drug-resistant (XDR)-Acinetobacter baumannii to fluoroquinolones
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.