Antimicrobial Resistance Patterns Among Healthcare-Associated Infections in a Pediatric Referral Center in Lima-Peru, 2015-2023
Abstract
Healthcare-associated infections (HAIs) results in increased morbidity and mortality rates, prolonged hospitalization and higher health care costs. While the surveillance of antibiotic-resistant bacteria involved in HAIs is important, there is limited data available in Latin America. The present study aimed to describe common pathogens and antimicrobial resistance patterns for HAIs among patients in a pediatric referral center.
Cross-sectional descriptive period study. Epidemiological surveillance data of HAIs were collected from hospitalized patients at the Instituto Nacional de Salud del Niño San Borja in Lima, Peru (2015-2023). Antimicrobial resistance data were analyzed for pathogens implicated in central line-associated bloodstream infections (CLABSIs), catheter-associated urinary tract infections (CAUTIs) and ventilator-associated pneumonias (VAPs). The dataset included comprehensive information on the clinical and epidemiological characteristics of patients, bacteria isolation sites and identification, as well as resistance profiles to antibiotics.
We included 1065 bacterial isolates from pediatric patients hospitalized with HAIs, of which 57.56% were male (n=613). The median age of the patients was 12 months (IQR: 2.04 – 60). Most of the isolates were collected from hospitalization (n=682, 64.04%). The most frequent type of HAIs was CLABSI (61.88%). Staphylococcus epidermidis (31%), Pseudomonas aeruginosa (19%), Klebsiella pneumoniae (15%) and Escherichia coli (12%)…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 682 participants or records.
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