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Animal models of migraine

Xiao-min Yang, Guang‐Xia Shi, Cun‐Zhi Liu

Int J Cerebrovasc Dis, 2012

Abstract

Migraine is the most common type of primary headache. The ideal animal models of migraine should be able to well replicate the key pathophysiological mechanism of migraine. According to the different pathogeneses, this article reviews the advances in research on the animal models of migraine from the aspect of making methods, determination criterion, advantages and disadvantages, and the scope of application, etc.

Key words:

Migraine Disorders; Disease Models, Animal; Cortical Spreading Depression

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