Effect of select yoga practices on clinical, biochemical, and quality of life outcomes in patients with migraine: A randomized controlled trial
Abstract
Migraine, a neurological disorder, is not only painful but also disabling and affects the daily life activities of the sufferer. According to the 2023 Global Burden of Disease Study, migraine remains a leading cause of headache-related years lived with disability worldwide, highlighting its significant global health burden. The objective of the study is to evaluate the effect of selected yoga practices on migraine-related disability, headache impact and intensity, cortisol, homocysteine, Vitamin B-12 (Vit B-12) levels, and overall well-being in migraine patients.
The current pilot study follows a randomized controlled trial design. A total of 32 migraine patients were randomly assigned, in equal numbers, into the Standard Care Group (G
rou
p I) and the Standard Care and Yoga Group (G
rou
p II). Assessments were conducted twice, once at baseline and again at post-intervention. Caregivers and outcome assessors were blinded. The data analysis was performed using descriptive statistics, paired, and independent
t
-tests.
Group II showed a significant reduction in Migraine Disability Assessment questionnaire (
p
= 0.001), headache impact test-6 (
p
< 0.0001), headache frequency (
p
= 0.001), pain intensity (
P
< 0.0001), and perceived stress (
p
< 0.0001). Significant improvement was observed in multiple domains of 36-item short-form, including physical functioning, emotional well-being, social functioning, and energy levels (all
p
< 0.05). Serum cortisol levels decreased…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 32 participants or records.
Read the paper
Related studies
- Calcium Ions in the Physiology and Pathology of the Central Nervous System
- AI-powered in silico twins: redefining precision medicine through simulation, personalization, and predictive healthcare
- In silico functional, structural and pathogenicity analysis of missense single nucleotide polymorphisms in human MCM6 gene
- In Silico drug repurposing pipeline using deep learning and structure based approaches in epilepsy
- Targeting serotonin receptors with phytochemicals – an in-silico study
- In silico exploration of anti-prostate cancer compounds from differential expressed genes
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.