Green Light and Transcranial Direct Current Stimulation in Migraine Patients: A Preliminary Randomized Control Trial
Abstract
Background: Migraine is a complex neurological condition characterized by a range of symptoms, such as intense to severe headaches, sensitivity to light and sound, and feelings of nausea and vomiting. The most common complaints regarding acute treatment are that medication causes adverse effects, that pain returns, or that pain relief is either too slow or inconsistent. Certain non-pharmacological methods, such as non-invasive neuromodulators, might be beneficial for alleviating migraines and require evidence for clinical judgment. Objective: The objective of the study was to determine the effects and compare the effects of green light and transcranial direct current stimulation on migraine frequency, intensity, impact, and quality of life. Methods: A randomized controlled trial was conducted with 69 migraine patients of both genders aged over 18 years, experiencing headache attacks lasting more than 4 h, characterized by pulsating and unilateral pain with an intensity of 5 or higher on the numeric pain scale. Active tDCS, sham tDCS, and green light, along with prescribed medications, were applied to Groups A, B, and C, respectively, for four weeks. The outcomes were measured at baseline, week 2, and week 4 for primary outcomes, including a structured headache diary, numeric pain scale, multidimensional pain inventory, and migraine-specific quality of life version 2.1 as a secondary variable. Results: Significant results were found for the NPS and MSQ with a p-value < 0.05…
How strong is the evidence?
Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 69 participants or records.
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