Assessment of Micronutrient Levels in Pediatric Migraine Patients
Abstract
Objective We aimed to evaluate the relationship between attack frequency and severity and serum levels of micronutrient in pediatric migraine patients. Methods Children at 2 hospitals from February to December 2022 diagnosed with migraine were reviewed. Results A total of 171 patients with a mean age of 14.3 ± 2.9 years were included in the study. The median 25(OH) vitamin D level was 15.6 μg/L in patients with an attack frequency of 1-3 per month versus 11.9 μg/L in those with more than 3 attacks per month ( P = .005). The median vitamin B 12 level was 386 ng/L in patients with attack duration of 2-6 hours versus 343.5 ng/L in those with an attack duration of 12-24 hours ( P = .048). The median ferritin level was 34 μg/L among patients not receiving prophylactic treatment and 24 μg/L among those receiving prophylactic treatment ( P = .019). Conclusions This study suggests that assessing micronutrient levels may be beneficial in children with migraine.
How strong is the evidence?
Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 171 participants or records.
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