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Low serum 25‐hydroxyvitamin D levels in migraine are not related to headache frequency: A case‐control study in patients with high‐frequency/chronic migraine

Marina Haro, G. Gárate, J. Hernandez, J. M. Olmos, María Muñoz, V. González-Quintanilla, Julio Pascual

Headache, 2025

3 citations

Abstract

Serum 25‐hydroxyvitamin D (25[OH]D) concentrations have been shown to be low in patients with migraine, but results are controversial regarding the current role of vitamin D in migraine severity. Using a case–control design, we aimed to evaluate serum 25(OH)D levels in a group of females with high‐frequency episodic migraine/chronic migraine (HF/CM) and analyze its association with headache frequency and serum calcitonin gene–related peptide (CGRP) levels.

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