Can serum neuropeptide levels help diagnose pediatric migraine? A prospective case–control study
Abstract
The objective of this study was to examine the serum levels of vasoactive neuropeptides (calcitonin gene‐related peptide [CGRP], pituitary adenylate cyclase‐activating peptide‐38 [PACAP‐38], substance P [SP], and vasoactive intestinal peptide [VIP], which have been linked to the pathophysiology of migraine in adults) in pediatric migraine without aura during both pain attacks and pain‐free periods and in a control group, with a view of evaluating their diagnostic value in pediatric migraine.
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