Evaluation of Brainstem Auditory Evoked Potentials in migraine patients during interictal phase: An observational cross-sectional study
Abstract
Background:
Migraine, the second most common type of primary headache disorder, is a complex neurological syndrome exhibiting a cyclical pattern. The attacks which are frequently associated with phonophobia, predispose patients to inflammatory auditory damage. Therefore, they remain hypersensitive to sound even during the headache free period. Frequent attacks increase the risk of otologic comorbidities early in life. Brainstem Evoked Response Audiometry (BERA), the most sensitive electrophysiological test of central nervous system dysfunction, was selected for this study to identify signal conduction defects within the auditory pathway up to brainstem projections during the interictal phase.
Aim:
This study aimed to evaluate Brainstem Auditory Evoked Potentials in terms of wave absolute latencies and interpeak latencies among migraine patients and compare them to healthy matched controls.
Methods:
This comparative, cross-sectional study was performed in the Physiology Department of SMS Medical College, Jaipur, Rajasthan, between April 2023 and June 2024 using click stimuli with rarefaction polarity. Seventy consenting participants, aged 20–40 years of both genders were divided into case and control groups, comprising of diagnosed migraine patients during the interictal phase recruited from the Neurology OPD, SMS hospital, Jaipur, and age and gender-matched healthy employees of SMS medical college, Jaipur, respectively. The brainstem potentials in terms of wave absolute and…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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