Assessing misophonia as a potential comorbidity in migraine patients compared to controls: a cross-sectional study
Abstract
Objective This study aimed to investigate the prevalence and symptom severity of misophonia among individuals with migraine, and to explore its clinical and psychological correlates. Background Misophonia is a neurobehavioral condition characterized by intense emotional and physiological reactions to specific everyday sounds, such as chewing or tapping. Although misophonia has been associated with increased sensory sensitivity and psychiatric comorbidities, its relationship with other sensory processing disorders-particularly migraine-remains underexplored. Methods In this cross-sectional study, 205 migraine patients and 205 healthy controls completed validated scales assessing misophonia symptoms, psychiatric comorbidities, and migraine-related disability. Statistical comparisons and univariate linear regression analyses were performed to identify predictors of misophonia. Results Our findings revealed a significantly higher prevalence of misophonia among individuals with migraine compared to healthy controls (44.9% vs. 17.6%). Misophonia symptoms were not only more common but also more severe in the migraine group. Migraine patients with comorbid misophonia scored significantly higher on the Headache Impact Test-6 and all components of the Migraine Disability Assessment Scale compared to those without misophonia. Sensory sensitivities such as photophobia, phonophobia, osmophobia, and allodynia were also more frequent and intense among migraine patients with misophonia.…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 205 participants or records.
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