PO-68 | Bipolar disorder spectrum and psychopathology in cluster headache compared to migraine: a cross-sectional study in a hospital headache clinic
Abstract
Background: Although numerous studies have been conducted over the last 20 years on the psychological characteristics and psychiatric comorbilities of primary headaches, migraine and tension-type headache, research focused less on cluster headache, a severe and rarer subtype.
Objectives: This study aims to assess psychopathological variables and to investigate the co-occurrence of bipolar disorder spectrum traits in patients with cluster headache disorder as compared with other primary headaches.
Methods: The cross-sectional phase of this observational study is in progress. Adult patients with cluster headache (73) or migraine (283) attending the Headache Outpatient Clinic of the Neurology Service (Department of Human Neuroscience AOU Policlinico Umberto I, Rome) were consecutively enrolled. An ad hoc questionnaire on socio-demographic variables and the following psychometric tools were administered: Headache Impact Test 6 (HIT-6), Mood Disorder Questionnaire (MDQ), Patient Health Questionnaire 9 (PHQ-9), Stress-related Vulnerability Scale 9 (SVS-9), items on alcohol/substance abuse (modified from M.I.N.I), Portrait Values Questionnaire 11 (PVQ-11) and MIDI Personality Trait Scales 30-item. Student t-test and Pearson chi-square test were used to compare the means of the two groups. Moreover, bivariate correlation analyses and multivariate linear regression were performed to identify mood swings predictors.
Results: Among all statistical analysis, the multivariate analysis…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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