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Efficacy of serum magnesium levels in migraine attack frequency and intensity: A clinical cross-sectional study

Ali Abdulridha Jabbar, Mahdi Tuama Khammas, H. Dixon

International Journal of Neurology Research, 2025

97 participants

Abstract

A neurological ailment that causes severe pain and pulsating sensations in patients, lasting for hours to days, is Migraine. However, in body metabolism and the functions of migraine patients, a major role is played by nutritional supplements. In particular, magnesium helps to reduce the Migraine Attack (MA) frequency and intensity. Nevertheless, the studies related to the association betwixt Serum Magnesium Levels (SML) and MAs are limited. Therefore, the present analysis intends to explore the efficiency of SMLs on MAs. Here, a total of 97 eligible participants are selected and systematized into a Control Group (CG) (n=62) and migraine group (n=35). The present research is conducted for six months continuously without any disruption by using the clinical cross-sectional studies. The role of serum magnesium in migraine severity is evaluated by adopting the quantitative approach. As per the outcomes, the magnesium level is lower in migraine group (1.62±0.39) than in the CG (2.19±0.31), which enhances the migraine severity and frequency. The study outcomes proved that the increasing SML decreases the migraine severity (29.76±1.12) and frequency (35.17±1.98) among the patients.

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 97 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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