Acinetobacter baumannii infections among patients in intensive care unit at the University College Hospital, Ibadan, Nigeria
Abstract
Background: Healthcare associated infections (HAIs), also known as nosocomial infections, pose a major safety risk for both patients and healthcare workers globally. Acinetobacter species are Gram-negative bacteria primarily associated with HAIs and have been implicated in outbreaks of infections such as ventilator-associated pneumonia, urinary tract infections, and septicaemia. The multi-drug resistance (MDR) nature of Acinetobacter species coupled with ability to survive for long periods in harsh conditions have made them of global health concern. Patients in intensive care units (ICUs) are highly susceptible to Acinetobacter infection. This study was designed to determine the prevalence and antibiotic resistance profiles of Acinetobacter isolates in infections among patients in the ICU of the University College Hospital, Ibadan, Nigeria.Methodology: A total of 120 consecutive patients were recruited into this study between April and December 2021 from whom blood samples, tracheal aspirates and catheter urine samples were obtained. Samples were obtained from patients who had spent a minimum of 48 hours in the ICU at the time of sample collection. The samples were cultured, and bacterial isolates were identified using standard microbiological methods. Antibiotic susceptibility testing was performed on all isolates by the disc diffusion method in line with the Clinical and Laboratory Standards Institute (CLSI) guideline. Data were analyzed using the Statistical Package for…
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