Atypical Presentations of Idiopathic Intracranial Hypertension in Clinical Practice. A Case Series
Abstract
Idiopathic intracranial hypertension (IIH) usually presents with headache, papilledema, and sixth nerve palsy,
but atypical manifestations can delay diagnosis. Atypical presentations in the present case series were
trigeminal neuralgia, focal seizures with Todd’s paresis, hypoglossal nerve palsy, intractable migraine like
headache, orthostatic intolerance and spontaneous CSF rhinorrhea. Most patients improved with medical
therapy, with only two requiring surgical intervention. These findings emphasize that atypical IIH is not
uncommon and that measuring cerebrospinal fluid opening pressure is essential for timely diagnosis.
How strong is the evidence?
Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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