Evidence Hub

Cervical Osteomyelitis With Epidural Abscess Overlooked In A Patient With Migraine And Idiopathic Intracranial Hypertension: A Case Report

Roy Sebastian

Annals Of Headache Medicine, 2025

Abstract

In patients with migraine or idiopathic intracranial hypertension (IIH) a worsening headache can often be attributed to an increase in intracranial pressure. Associated symptoms like new onset or worsening neck pain may be masked by this diagnosis, delaying identification of other serious conditions like cervical osteomyelitis. We present a female in her thirties with a medical history of episodic migraine, idiopathic intracranial hypertension without papilledema (IIHWOP), and type two diabetes mellitus, who developed worsening headaches with neck pain, photophobia, vertigo, and weight loss. Standard migraine therapies were ineffective. Neurological exams, fundoscopy, brain and vascular imaging, and lumbar puncture were unremarkable. A cervical spine MRI revealed findings consistent with cervical osteomyelitis and an epidural abscess. Cultures confirmed methicillin-resistant Staphylococcus aureus (MRSA). She was treated with antibiotics and monitored by infectious disease and neurology. Follow-up imaging showed improvement, and she continued conservative treatment with close specialist follow-up. This case underscores the importance of maintaining a broad differential diagnosis in patients with worsening headache features, particularly when associated with red flag symptoms such as neck pain and systemic signs, to avoid delays in diagnosing potentially life-threatening conditions such as spinal infections.

How strong is the evidence?

Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free