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Eyebrow bleeding as a rare migraine symptom: a case report

Azita Tavasoli, Mohammad Rezazadeh, Maryam Kachuei

Annals of Medicine and Surgery, 2024

Abstract

This case report documents a rare presentation of eyebrow bleeding occurring during migraine episodes in a 10-year-old girl, highlighting atypical signs associated with the disorder. Despite her normal neurological examinations and imaging studies, the patient experienced recurrent, severe headaches accompanied by localized bleeding and red spots on the forehead. This unusual symptomatology suggests potential underlying neurovascular and neuroinflammatory mechanisms, necessitating heightened awareness among healthcare providers. Following treatment with Coenzyme Q10, Vitamin B2, and Cyproheptadine, both headache frequency and symptom intensity significantly improved. This case underscores the importance of comprehensive evaluation and recognition of uncommon migraine manifestations in clinical practice.

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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