Identifying key risk factors for the recurrence of benign paroxysmal positional vertigo following successful canalith repositioning maneuvers: a meta analysis
Abstract
Background: An increasing occurrence trend of benign paroxysmal positional vertigo (BPPV) after successful canalith repositioning maneuvers was observed; however, the risk elements for the occurrence of this disease remain undefined. We aimed to conduct a meta-analysis of BPPV occurrence-associated risk factors reported.
Methods: A comprehensive search in MEDLINE, EMBASE, PubMed, Springer, and the Cochrane Library up to March 31, 2024. The meta-analysis was carried out with STATA 16.0. Quality evaluation of the articles was performed with the Newcastle-Ottawa Scales (NOS). Data were pooled by a random-effects model. The meta-analysis was registered at INPLASY (202430045).
Results: Seventeen studies with 229 patients were included in the present analysis. The recurrence rate of BPPV after Canalith repositioning procedure (CRP) or Epley maneuver in subjects with hypertension [standardized mean difference (SMD) = 0.88,95% confidence interval (CI) (0.81-0.96), P = 0.00], Meniere's disease [SMD = 0.84, 95%CI (0.57-1.10), P = 0.00], head trauma [SMD = 0.48, 95%CI (0.34-0.63), P = 0.00], diabetes mellitus (DM) [SMD = 0.87, 95%CI (0.80-0.94), P = 0.00], advanced age [SMD = 0.18, 95%CI (0.08-0.28), P = 0.00], osteoporosis [SMD = 0.32, 95%CI (0.20-0.43), P = 0.00], female gender [SMD = 0.53, 95%CI (0.40-0.67), P = 0.00], migraine headache [SMD = 0.20, 95%CI (0.06-0.35), P = 0.01], and vitamin D deficiency [OR = 0.29, 95%CI (0.18-0.40), P = 0.00] were appreciably higher than those in…
How strong is the evidence?
Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 229 participants or records.
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