Traditional Chinese Medicine for Acute Migraine: A Systematic Review and Meta-Analysis
Abstract
Objectives: A meta-analysis of traditional Chinese medicine in the treatment of acute migraine was conducted to obtain a consistent evaluation of its efficacy. Methods: The search databases were China National Knowledge Infrastructure (CNKI), Wanfang, VIP, Chinese Biomedical Literature Database (CBM) and PubMed. The publication time of randomized controlled studies (RCT) documents is limited to before June 30, 2023. Results: Data from 399 patients from 5 RCTs were included. Compared with Western medicine, Traditional Chinese medicine has a higher efficacy ([RR=0.81, 95%CI (0.75, 0.89), P<0.00001]), a lower adverse reaction rate ([RR=1.37, 95%CI (0.74, 2.54), P=0.32]) and an improved VAS ([MD=-1.37, 95%CI (-2.00, -0.75), P<0.00001]). Conclusion: Traditional Chinese medicine in the treatment of acute migraine can enhance clinical efficacy, reduce treatment side effects, and improve patients’ visual analogue score.
How strong is the evidence?
Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 399 participants or records.
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