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Evaluating a non-pharmacological treatment for primary premature ejaculation patients with low sexual frequency: a retrospective study on vacuum negative pressure hydropneumatic/pneumatic bubble massage

Gao QQ, He CB, Wang B, Dai YT, Yang BB, Zhao XZ

Sexual medicine, 2025

42 participants

Abstract

Background: Premature ejaculation (PE) is a common male sexual dysfunction with treatment limitations including side effects and partner dependency.

Aim: To evaluate vacuum negative pressure hydropneumatic/pneumatic bubble massage (VNPHP/PBM) efficacy in primary PE (PPE) patients stratified by sexual frequency, focusing on subjective low-frequency (avoidance due to PE) vs objective low-frequency subgroups.

Methods: Retrospective analysis of 42 PPE patients: 22 low-frequency (LF; <4 intercourse/month) including 13 subjective (sub-LF) and 9 objective (ob-LF) vs 20 non-low-frequency (NLF; ≥4/month).

Outcomes: Primary: intravaginal ejaculation latency time (IELT); secondary: Premature Ejaculation Diagnostic Tool (PEDT), Self-Rating Anxiety Scale (SAS) scores, and sexual frequency changes at 4 weeks.

Results: Both groups showed significant improvements in IELT, PEDT, and SAS scores (P P = .03), SAS reduction (30.95 ± 9.57 vs 38.45 ± 8.85, P = .01), and sexual frequency increase (0.50 [0.00, 4.00] vs 1.00 [1.00, 2.00], P = .02). Crucially, sub-LF patients exhibited dramatic sexual frequency normalization (6.00 [4.00, 7.50] vs 2.00 [1.00, 2.00], P P = .56). No adverse events.

Clinical implications: Vacuum negative pressure hydropneumatic/pneumatic bubble massage is a partner-independent therapy that not only improves ejaculatory control but also restores sexual activity in patients avoiding intercourse due to PE-related anxiety.

Strengths and limitations: Strengths: First study…

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