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A randomized controlled Trial of telerehabilitation intervention for acute ischemic stroke patients Post-Discharge

Shihao Sun, Yu Li, Gang Zhang, Yong Zhang, Jun Dong

Journal of clinical neuroscience, 2025

200 participants · 13 citations

Abstract

BACKGROUND

The acute ischemic stroke (AIS) represents a significant contributor to global disability and mortality rates. Effective rehabilitation interventions play a critical role in enhancing patients' functional recovery and overall quality of life. With the advancement of telemedicine technology, post-discharge telerehabilitation interventions are becoming increasingly feasible, yet their efficacy requires validation through randomized controlled trials (RCT). This study aimed to evaluate the efficacy of a 12-week telerehabilitation program compared to standard post-discharge care in AIS patients.

METHODS

This study employed a randomized controlled design, enrolling 200 patients who had been discharged after an AIS. Participants were randomly assigned to either the intervention group or the control group in a 1:1 ratio. The intervention group received a 12-week telerehabilitation program, which included a personalized rehabilitation training plan, regular video consultations, and health education. The control group received standard post-discharge care, which consisted of a rehabilitation manual and biweekly outpatient follow-ups for up to 12 weeks. The primary outcome measure was the Barthel Index, assessing patients' ability to perform activities of daily living. Secondary outcome measures included the modified Rankin Scale (mRS, assessing the degree of disability), Hamilton Depression Rating Scale (HAMD, assessing the patients' mental health status), and World Health…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 200 participants or records.

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