Immediate Autotransplantation of Mature Third Molars to Bilateral Mandibular First Molars With Large Periapical Lesions: A Case Report
Abstract
Previously reported protocols suggested that the transplantation of teeth should be delayed if the recipient site presents large periapical lesions. The presented case is a pioneering attempt to conduct mature third molar transplantation immediately after the extraction of mandibular first molars accompanied by large periradicular lesions with the guidance of computer‐designed 3D‐printed replicas and with the utilization of concentrated growth factor (CGF) so as to avoid the use of synthetic bone substitutes and secondary surgical procedures. A 24‐year‐old female patient in generally good health was presented with pain and swelling of bilateral mandibular first molars accompanied by a sinus tract. Cone‐beam computed tomography (CBCT) revealed 16 * 10 mm and 13 * 7 mm low density, respectively, in the periapical area of #46 and #36. After confirmation of the feasibility of transplanting the mandibular third molars to the first molars with the evaluation by CBCT, patient's consent was obtained. Based on patient's CBCT, individual 3D‐printed replicas of the mandibular third molars were fabricated and CGF was collected by centrifugation. Autogenous tooth transplantation (ATT) was performed immediately after the removal of the first molars and curettage of periapical lesions. The periapical bone defect was filled with CGF membranes. After the surgery, healing conditions were monitored. At 18‐month follow‐up, both transplanted teeth presented with stable healing without any…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials
- Tocilizumab in patients with severe COVID-19: a retrospective cohort study
- A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study
- Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study
- Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
- Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.