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Hypothyroidism and Hyperthyroidism in an Adolescent With Complex Congenital Heart Disease Exposed to Iodinated Contrast Media: Case Report

Elizabeth S Sandberg, J. Fisher

Case Reports in Endocrinology, 2025

3 citations

Abstract

Introduction: Jod‐Basedow syndrome and iodine‐induced hypothyroidism are rare but clinically significant complications of iodine exposure. We report a unique case of a 14‐year‐old boy with congenital heart disease, who developed sequential iodine‐induced hypothyroidism due to failure to escape from the Wolff–Chaikoff effect, followed by hyperthyroidism (Jod‐Basedow syndrome) after additional exposure to iodinated contrast.

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