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Indian Journal of Psychiatry, 2026

69 participants

Abstract

Adverse childhood experiences and substance use disorder in adult life in patients attending a tertiary care institute in north-eastern India Aahel Bandyopadhyay King George Medical University, Lucknow, Uttar Pradesh, India Background: Substance use disorder (SUD) is a widely prevalent condition worldwide. Studies have found that childhood adversities are one of the key factors leading to the changes in neural networks, impaired endocrine and immune system development resulting in chronic physiological dysfunction. There are only a few studies reporting relationship between adverse childhood experiences (ACEs) and SUD in India. Aim: To assess the impact (if any) of adverse childhood experiences on substance use disorder in adult life. Methods: Observational and descriptive study with sample size 150 was conducted among patients having SUD of age group 18-60 years attending Department of Psychiatry, Regional Institute of Medical Sciences, Imphal, Manipur during May 2022 to June 2024. Study tools were semi structured questionnaire for socio demographic profile, DSM-5 diagnostic criteria for diagnosis and severity of SUD, semi-structured proforma for type and pattern of substance use, Adverse Childhood Experiences International Questionnaire for assessing childhood trauma of subjects. Results: Among the subjects with alcohol and opioid use disorder, significant difference existed between those who had experienced ACEs and who had not in the domains of community violence,…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 69 participants or records.

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