Evidence Hub

Tobacco Control Messages for Individuals Who Use Both Cigarettes and E-cigarettes: A Randomized Trial Comparing Biomarker Outcome with Cessation Experience Narratives

R. Subramanian, Kaeli Samson, H. Dai

Tobacco Control, 2025

489 participants

Abstract

Background Dual use of e-cigarettes and cigarettes is prevalent among US adults, increasing nicotine addiction and health risks. This study investigated what type of narrative messages would be more effective in encouraging individuals who use both e-cigarettes and cigarettes to quit both smoking and vaping. Methods We conducted an online between-subjects randomised experiment on individuals who currently use both e-cigarettes and cigarettes (n=489). The ‘biomarker outcome’ narrative group viewed a ‘why-quit’ message that highlighted a decrease in biomarkers of toxicant exposure on quitting smoking and vaping; the ‘cessation experience’ narrative group viewed a ‘how-to-quit’ message that highlighted strategies for quitting smoking and vaping. Multivariable regressions were conducted to evaluate message effects on motivation to quit smoking and vaping based on perceived importance, commitment and readiness (range: 0–10). Mediation analyses were performed to assess pathways from messages through emotional responses to motivation to quit. Results As compared with viewing the ‘cessation experience’ narrative, exposure to the ‘biomarker outcome’ narrative led to larger increases in the motivation to quit smoking (adjusted β (SE)=0.3 (0.1), p=0.02) and vaping (adjusted β (SE)=0.5 (0.1), p=0.003). Individuals who were exposed to the ‘biomarker outcome’ narrative reported higher negative emotions and lower positive emotions than those in the ‘cessation experience’ narrative group.…

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 489 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free