The influence of various nicotine and tobacco delivery methods on the course of bronchial asthma: Preliminary research results
Abstract
Introduction.
Smoking, as one of the significant modifiable risk factors, is being actively studied in the context of asthma.
Aim.
To assess the effect of electronic cigarettes and electronic tobacco heating devices on the course and control of bronchial asthma, as well as changes on inflammatory profiles. An important aspect is to assess the profile of the patient using smoking devices in order to optimize the therapy selection and patient management strategies.
Materials and methods.
An open-label observational clinical trial including medical history assessment, physical examination, completion of the Asthma Control Questionnaire (ACT) and the Asthma Quality of Life Questionnaire (AQLQ), clinical functional examination, and venous blood sampling for biomarker analysis. The study included patients aged 18–45 years with a confirmed diagnosis of bronchial asthma for at least 12 months.
Results.
84 patients were included in the study (82 men and 2 women), with a mean age of 21.99 ± 2.38 years. Of these, 32 patients were non-smokers, while 52 reported using various nicotine and tobacco products. Among the smokers, 30 (57.7%) used two or more types of smoking devices. Passive smoking exposure was reported across all groups, with 69 patients (82.1%) indicating regular exposure to environmental tobacco smoke from their surroundings. Smokers were more frequently exposed to passive smoking. The average age of smoking initiation is 16 years. In both groups, according to ACT data,…
Read the paper
Related studies
- Tobacco and COPD: presenting the World Health Organization (WHO) Tobacco Knowledge Summary
- Comparative effects of e-cigarette smoking on periodontal status, salivary pH, and cotinine levels
- Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review
- Influence of gestational window on offspring vascular health in rodents with in utero exposure to electronic cigarettes
- Natural products as kinase inhibitors in lung cancer: molecular mechanisms, therapeutic potential, and clinical trials
- Nicotine in electronic cigarettes
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.