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On the role of monitoring biomarkers of tobacco consumption and nicotine-containing products in the prevention of smoking among adolescents in a metropolis

Polina Nikolaevna Bol'shakova, Sergey N. Cherkasov, A. N. Isaev, OOO «DNKOM», Yu. O. Isaeva, OOO «DNKOM»

Manager Zdravookhranenia, 2025

34 participants · 1 citation

Abstract

Transformation of conventional cigarettes into innovative nicotine-containing products (NP) with an elegant design and various flavors is aimed at teenagers and women. The strategy of the state anti-tobacco policy and measures to popularize the culture of health have increased the role of the family in smoking prevention. Objective of the study: evaluation of the effectiveness of monitoring the consumption of tobacco and nicotine-containing products using biomarkers in the prevention of smoking among adolescents in a metropolitan area. Material and methods. To assess the effectiveness of monitoring the consumption of tobacco and nicotine-containing products using biomarkers in the prevention of smoking in adolescents in a metropolitan area. Material and methods: an observational analytical retrospective study was conducted. In the laboratory of OOO «DNKOM» (Moscow), the level of nicotine, cotinine and a biomarker of the effect of ES and vapes were measured in the middle portion of morning urine of adolescents. The analysis was performed by gas chromatography/mass spectrometry on an Agilent 6890N instrument with an Agilent 5973N mass-selective detector (USA). Statistical processing was performed using the standard Microsoft Office package, Excel using Student’s t-test, differences were considered significant at p <0.05. Results and discussion. The results of measuring tobacco, ES and vaping biomarkers in the urine of 34 people aged 9–17 years (average age 14.03±0.27 years)…

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