Factors Influencing the Lung Cancer Incidence in China: A Meta-Analysis
Abstract
Aim: The aim of the study was to systematically evaluate the main factors associated with lung cancer incidence in China and provide reference for developing successful lung cancer interventions and accelerating progress against cancer. Methods: All publications related to the influencing factors of lung cancer incidence were retrieved from four databases from their date of inception through September 2022. Eight Medical Subject Headings and corresponding keywords were utilized to identify eligible trials in China National Knowledge Infrastructure (CNKI), Wanfang Database, Chinese Scientific Journals Database (VIP), and China Biology Medicine Database (CBM). The heterogeneity test and meta-analysis were conducted using Review Manager (RevMan, version 5.4) software. This study was designed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols. Results: Fourteen studies, published from 2000 to 2019, have been chosen and incorporated in a meta-analysis. The mean total quality score across the included studies was 7, with a range of 6–8. The findings of the meta-analysis demonstrated that smoking (odds ratio = 2.46, 95% confidence interval: 1.94–3.11), passive smoking (odds ratio = 2.44, 95% confidence interval: 2.13–2.80), lung/respiratory disease (odds ratio = 2.66, 95% confidence interval: 1.82–3.89), family history of tumor (odds ratio = 2.79, 95% confidence interval: 1.80–4.32), oil fume (odds ratio = 1.91, 95% confidence interval:…
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Evidence Hub reads this as a meta-analysis. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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