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Correspondence on ‘Interleukin-6 receptor blockade with subcutaneous tocilizumab in severe COVID-19 pneumonia and hyperinflammation: a case–control study’ by Potere et al

L. Buckley

Annals of the Rheumatic Diseases, 2020

2,104 participants · 1 citation

Abstract

I read with interest the recent case–control study by Potere et al , which describes the potential efficacy and safety of tocilizumab in patients with severe COVID-19 pneumonia and hyperinflammation.1 Since publication of this analysis, new information on anti-inflammatory therapies in COVID-19 has become available. The RECOVERY trial randomised 2104 patients with COVID-19 to receive dexamethasone 6 mg daily or usual care for up to 10 days. …

How strong is the evidence?

Evidence Hub reads this as a randomized trial. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 2,104 participants or records.

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