Treatment profiles and risk factors for clinical outcomes of confirmed COVID-19 and pneumonia patients at fatmawati general hospital jakarta
Abstract
Objectives: This study aimed to investigate the treatment profiles and the risk factor for clinical outcomes of confirmed coronavirus disease-19 (COVID-19) and pneumonia patients at Fatmawati General Hospital Jakarta.
Methods: This research was conducted using a cross-sectional design at Fatmawati General Hospital Jakarta. A total of 72 adults COVID-19 confirmed patients with pneumonia diagnosis from March to December 2020 were included in our study. Data were collected retrospectively by the patients’ medical record.
Results: The percentage of critical or severe confirmed COVID-19 with pneumonia inpatients (66.7%) was higher than those who were having non-severe diseases (33.3%). 36 (50%) death were reported in our patient population. Patients received antiviral, antibiotics, and steroids during a treatment period. The most common antibiotic regimens were levofloxacin intravenous (IV) (18.8%) and azithromycin per oral (PO) (13.9%). Oseltamivir (83.3%) was the most frequently prescribed antiviral for the patients. A total of 41.7% of patients used steroids. In multivariable logistic regression analyses, the severity of COVID-19 disease was the only predictive factor of death in COVID-19 and pneumonia patients (p<0.001, OR=26.714, 95% confidence intervals: 5.526–129.135).
Conclusion: Some drugs (antiviral, antibiotics, and steroids) have been prescribed to the confirmed COVID-19 with pneumonia patients. Oseltamivir and levofloxacin were the widely used antiviral and…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 72 participants or records.
Read the paper
Related studies
- Severe clinical outcomes of COVID-19 associated with proton pump inhibitors: a nationwide cohort study with propensity score matching
- Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors
- Inhalable Mannosylated Rifampicin–Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
- Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)
- GC-MS Analysis and Biomedical Therapy of Oil from n-Hexane Fraction of Scutellaria edelbergii Rech. f.: In Vitro, In Vivo, and In Silico Approach
- Novel Pharmacokinetic/Pharmacodynamic Parameters Quantify the Exposure–Effect Relationship of Levofloxacin against Fluoroquinolone-Resistant Escherichia coli
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.