C16-08 Association of Nicotine and Cannabis Vaping and Respiratory Symptoms in U.S. Young Adults: The American Lung Association Lung Health Cohort Study
Abstract
Vaping is an endemic phenomenon in the United States, with greatest increases in recent prevalence occurring in young adults. Vaping is known to be associated with respiratory harm, including symptoms and prevalent diagnoses of asthma and COPD; however, the relative health impacts of the two most commonly vaped substances - cannabis and nicotine - have not been differentiated in young adults. Therefore, there is a need to characterize rates of nicotine, cannabis, and dual use and their contribution to concurrent respiratory symptoms, which may have implications for counseling and cessation strategies.
We performed a cross-sectional analysis of vaping practices and patterns in the American Lung Association Lung Health Cohort, which enrolled US adults aged 25-35 years without severe cardiopulmonary disease starting in 2021 in 28 sites in the US. Participants responded to surveys about vaping at study entry and were classified as current (past 30 day), former, or never use of cannabis and nicotine vaping. Associations of vaping status (current, former, or never) and current product (nicotine, cannabis, or both) with having at least one current respiratory symptom (cough, phlegm, wheezing, shortness of breath) were assessed using multivariable logistic regression, adjusted for sex, ethnicity, race, smoking, and education.
The study enrolled 2,844 participants (median age 29, 64% female, 28% Hispanic or Latino, 19% Black). Of these, 5% were current, and 33% former, combustible…
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