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Impact of electronic cigarette USE on quality of life and autonomic nervous system function in young adults

I. Vysochyna, T. Yashkina, V. Kramarchuk

Clinical and Preventive Medicine, 2025

92 participants · 1 citation

Abstract

Introduction. The global decline in traditional tobacco smoking has been accompanied by the rise of heated tobacco products and electronic cigarettes, marketed as safer alternatives. Despite their popularity among youth, especially due to aggressive marketing and appealing flavors, the long-term health effects of heated tobacco products remain insufficiently studied.

Aim. To evaluate the effects of heated tobacco product use on the quality of life and autonomic nervous system function in healthy young adults using the SF-36 and Wayne questionnaires, with a focus on gender-specific differences.

Materials and methods. This case-control study involved 92 participants divided into two groups: 66 heated tobacco products users and 26 non-smokers. Inclusion criteria for main group comprised daily use of these devices for up to five years, somatic health, and a body mass index within normal limits. Non-smokers had no active or passive exposure to tobacco products. Quality of life was evaluated using the SF-36 questionnaire, which measures physical and mental health components through eight subscales. The nervous function was assessed using the Wayne questionnaire, which evaluates the balance between sympathetic and parasympathetic regulation.

Results. Heated tobacco product users demonstrated significantly lower quality of life scores compared to non-smokers, particularly in physical and mental health components. Women showed more pronounced declines in role-physical functioning,…

How strong is the evidence?

Evidence Hub reads this as a case-control, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 92 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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