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A Case of Colonic Vasculitis Mimicking IBD in a 45-Year-Old Female: A Clinical Case Report

Laghfiri N, E. M., Jallouli A, Nacir O, Lairani Fz, A. A, Oubaha S, Samlani Z et al.

Archives of Clinical Gastroenterology, 2025

Abstract

Colonic vasculitis is a rare condition that can mimic Inflammatory Bowel Disease (IBD) due to its clinical presentation. We report the case of a 45-year-old female, a passive smoker, presenting with isolated colonic vasculitis manifested by bloody mucus diarrhea. Investigations, including colonoscopy and histopathology, allowed the differentiation of this vasculitis from IBD. The patient was successfully treated with systemic corticosteroid therapy, leading to significant clinical improvement. This case highlights the importance of precise diagnosis in atypical presentations and the potential role of passive smoking in triggering such pathologies.

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