Aggressive Squamous Cell Lung Carcinoma in a Long-Term E-Cigarette User with Intracardiac Complications: A Case Report
Abstract
Patient: Male, 51-year-old Final Diagnosis: Squamous cell carcinoma Symptoms: Chest discomfort • dyspnea • hemoptysis • weight loss Clinical Procedure: Bronchoscopy • CT angiography • transesophageal echocardiogram Specialty: Cardiology • General and Internal Medicine • Oncology • Pulmonology Objective: Rare disease Background The use of electronic nicotine delivery systems (ENDS), commonly referred to as electronic cigarettes (e-cigarettes), involves inhaling a mixture of heated nicotine, glycerin, propylene glycol, and flavorings. There has been increasing concern about the harm of long-term use of e-cigarettes, including an association with the development and progression of lung cancer. This report describes a 51-year-old male former cigarette smoker with an 11-year history of e-cigarette use (vaping) presenting with an aggressive advanced squamous cell carcinoma of the lung, which was fatal. Case Report A 51-year-old man with type 2 diabetes, hypertension, a 10-pack-year smoking history, and 11 years of e-cigarette use presented with hemoptysis, weight loss, chest discomfort, and worsening dyspnea. Initial imaging revealed a large left upper-lobe mass. Transesophageal echocardiography (TEE) showed a large tumor thrombus in the left atrium. Biopsy confirmed poorly differentiated squamous cell carcinoma (SCC). He was stabilized and discharged, but returned 2 weeks later with worsening symptoms. Imaging showed significant tumor progression. Bronchoscopy revealed worsening…
How strong is the evidence?
Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
Read the paper
Related studies
- Tobacco and COPD: presenting the World Health Organization (WHO) Tobacco Knowledge Summary
- Comparative effects of e-cigarette smoking on periodontal status, salivary pH, and cotinine levels
- Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review
- Influence of gestational window on offspring vascular health in rodents with in utero exposure to electronic cigarettes
- Natural products as kinase inhibitors in lung cancer: molecular mechanisms, therapeutic potential, and clinical trials
- Nicotine in electronic cigarettes
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.