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E-cigarette or vaping use-associated lung injury

L. Povalyaeva, E. Borodulina, B. Borodulin, A. Kolesnikova, M. A. Vakhlyaev, N. V. Krasnov, E. Roslikova, N. Skoptsova et al.

PULMONOLOGIYA, 2026

Abstract

Over the past decade, the rapid growth in popularity of electronic nicotine delivery systems has led to an increase in lung injury cases and a new condition known as e-cigarette or vaping use-associated lung injury (EVALI).

The aim

of this study was to present the first case of e-cigaretteassociated lung injury reported in a hospital setting.

Results

. A young patient was admitted to the hospital on an emergency basis with severe respiratory complaints. Initial radiographic findings were normal. Over the course of one year, the patient developed progressive respiratory failure, leading to widespread pneumofibrosis, which ultimately resulted in death.

Conclusion

. Based on the identified combination of emphysema, pulmonary fibrosis, and histologically confirmed alveolitis, along with a history of e-cigarette smoking, a diagnosis of toxic acute lung injury (EVALI syndrome) with a histological pattern of diffuse alveolar damage, resulting in pulmonary fibrosis, was verified.

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