Comparing the Effects of e-Cigarettes and Traditional Cigarettes on Asthma in Adolescents: A Systematic Review
Abstract
Asthma is one of the most common chronic diseases among teenagers, and environmental factors such as smoking worsen the condition. The growing popularity of e-cigarettes raises concerns over their potential effects on asthma in adolescents compared to traditional cigarettes. This systematic review sought to evaluate the differences between e-cigarettes and traditional cigarettes in relation to asthma diagnosis, exacerbations, and symptoms in adolescents using quantitative studies conducted between 2015 and July 2025. Following PRISMA guidelines, we searched PubMed, Scopus, and the Web of Science and found 427 articles. After removing duplicates (n=188) and ineligible studies (n=229), we included 10 studies (1 cohort, 9 cross-sectional). Inclusion criteria included focus on adolescents, comparison of e-cigarettes and traditional cigarettes, and studies with asthma-related outcomes. Study quality was evaluated using Newcastle-Ottawa Scale (NOS; scores 6-8/10). Extracted data were narratively synthesized and comparatively analyzed across exposure groups due to heterogeneity in study design, outcomes, and effect measures. e-cigarettes were found to increase the likelihood of developing asthma more than traditional cigarettes among adolescents (AOR=1.10-1.30). Statistically significant relationships were also detected between exacerbations of asthma and e-cigarette use (AOR=2.13; APR=1.54-1.85). The impact of traditional cigarettes (AOR=0.80-8.49) was mixed. The highest risk was…
How strong is the evidence?
Evidence Hub reads this as a systematic review, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid. Reported size: 229 participants or records.
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