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Case report: Metformin-induced hemolytic anemia in a glucose-6-phosphate dehydrogenase-deficient patient

Salamat AM, Ammar HM, Alsagheir AI, Mushcab HS

The Journal of international medical research, 2025

Abstract

This case report describes a male patient in his early 60s with a documented history of glucose-6-phosphate dehydrogenase deficiency, who developed significant hemolytic anemia following the initiation of metformin therapy for newly diagnosed type 2 diabetes mellitus.

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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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