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Severe Metformin‐Associated Lactic Acidosis—A Case Report

Elizabet Artinyan, G. Nikolov, Evelina Valcheva, Prajwol Baniya, Danika Sritharan, A. Khan, Marina Vaysilova, Nikolay Dimov

Clinical Case Reports, 2026

Abstract

Metformin, a widely prescribed and generally safe drug for diabetes mellitus, can rarely lead to metformin‐associated lactic acidosis—a severe, potentially fatal complication. Early recognition, emergency hemodialysis, and supportive management are crucial for favorable outcomes, highlighting the importance of prompt diagnosis and intervention to reduce mortality in this critical condition.

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