Determination of levofloxacin in levofloxacin lactate injection by HPLC
Abstract
Aim To develop a method for determining the contents of levofloxacin in levofloxacin lactate injection.Methods The analyt-ical column was a Hypersil VP-ODS(4.6 mm × 250 mm,5 μm).The mobile phase consisted of triethanolamine-methyl cyanides(82: 18).The flow rate was 1.0 ml.min-1and the column temperature was 40℃.The detection wavelengths of luteolin was at 286 nm.Re-sults The calibration curves of luteolin was in good linearity over the rangs from 1.73 to 15.61 mg.L-1and the average recovery was 100.21%.Conclusion The method is simple,rapid,reliable and can be used for the drug control.
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