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Levofloxacin Treatment Failure inHaemophilus influenzaePneumonia

Teresa Bastida, Maria Dolores Pérez-Vázquez, José Campos, María Cristina Cortés-Lletget, Federico Román, Fé Tubau, Adela G. de la Campa, Carles Alonso-Tarrés

Emerging infectious diseases, 2003

45 citations

Abstract

We describe the first case of failure of oral levofloxacin treatment of community-acquired pneumonia caused by Haemophilus influenzae. The strain showed cross-resistance to fluoroquinolones and carried four mutations in quinolone resistance-determining regions of DNA gyrase and topoisomerase IV genes.

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