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Levofloxacin in treating infective disease in 60 patients

Deng Ai

Chinese Journal of New Drugs and Clinical Remedies, 2000

60 participants

Abstract

AIM: To study the efficiency of levofloxacin and compare with ciprofloxacin in treating infective disease. METHODS: Ninety patients with infective disease were divided into two groups. The levofloxacin group of 60 patients (M 38, F 22; age 67 a±s 10 a) were treated with levofloxacin lactate injection. Among them the thirty patients were given 200 mg qd, and another thirty patients were given 100 mg bid. The control group of 30 patients (M 13,F 17; age 57 a±6 a) were given ciprofloxacin lactate injection 200 mg bid. Three groups all given by iv, drip×714d. RESULTS: The cure rates were 85 % in levofloxacin group and 53 % in the control group (P0.05). The cure rates and effective rates were 83 % and 97 % in the first thirty patients and 87 % and 90 % in the second thirty patients (P 0.05). CONCLUSION: Lavofloxacin have better effective than ciprofloxacin in the treatment of infective disease, and the similar efficiency can be observed with the same dose·d -1 qd or bid.

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