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Response to Letter to the Editor: Meta-Analysis of the Long-term Efficacy and Tolerance of Tadalafil Daily Compared With Tadalafil On-Demand in Treating Men With Erectile Dysfunction

Zhong-Bao Zhou, Zhen-Li Gao, Ji-Tao Wu, Yuanshan Cui

Sexual Medicine, 2020

Abstract

The reader said, "In the results section, the authors reported that the tadalafil daily group had a greater increase of IIEF-EF (MD 1⁄4 1.24; 95% CI 1⁄4 0.03e2.44; P 1⁄4 0.04), SEP2 (MD 10.08; 95% CI 1⁄4 9.15e11.01; P < 0.00001) and SEP3 (MD 8.19; 95% CI 1⁄4 2.09e14.29; P < 0.00001) in comparison to tadalafil on-demand, which suggest the superiority of tadalafil daily. However, when we show the results using the forests plots figures, it could be interpreted as the other way due to technical setting of describing forest plot."

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